The people behind the ideas.
The ideas behind the companies.
![MotherDuck](https://www.madrona.com/wp-content/uploads/2024/07/Transparent-Jordan-MotherDuck.png)
MotherDuck’s
Joran Tigani
on shaping serverless data with DuckDB ![Runway](https://www.madrona.com/wp-content/uploads/2024/06/Cris-Runway-transprent.png)
Runway’s
Cristóbal Valenzuela
on AI-driven art and lifelong learning ![Rec Room](https://www.madrona.com/wp-content/uploads/2024/07/Transparent-Nick-Fajt.png)
Rec Room’s
Nick Fajt
on democratizing game development ![Common Room](https://www.madrona.com/wp-content/uploads/2022/09/LindaLian_2_FPO-sm.png)
Common Room’s
Linda Lian
on integrating community into your company ![Pulumi](https://www.madrona.com/wp-content/uploads/2024/02/Joe-Duffy.png)
Pulumi’s
Joe Duffy
on bringing more power to developers ![Statsig](https://www.madrona.com/wp-content/uploads/2023/11/Vijaye-Statsig-3.png)
Statsig’s
Vijaye Raji
on using data to build better products Company List
Early
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Envisagenics is an Artificial Intelligence-driven biotechnology company that focuses on the discovery of novel RNA splicing variants that cause cancer and other genetic diseases. Its principal technology is the SpliceCore® discovery platform. The platform re-envisions the human genome with a validated exon-centric approach, combined with machine learning algorithms and high-performance computing. It is up to 250 times more likely to discover novel targets than gene-centric discovery tools. Using innovative technology and RNA analysis expertise, Envisagenics accelerates the development of highly specific therapeutics that modulate RNA splicing events that drive pathogenesis of oncology, neurodegenerative, and metabolic disorders.Initial Investment2018Envisagenics is an Artificial Intelligence-driven biotechnology company that focuses on the discovery of novel RNA splicing variants that cause cancer and other genetic diseases. Its principal technology is the SpliceCore® discovery platform. The platform re-envisions the human genome with a validated exon-centric approach, combined with machine learning algorithms and high-performance computing. It is up to 250 times more likely to discover novel targets than gene-centric discovery tools. Using innovative technology and RNA analysis expertise, Envisagenics accelerates the development of highly specific therapeutics that modulate RNA splicing events that drive pathogenesis of oncology, neurodegenerative, and metabolic disorders.
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Based in Seattle, Washington, Nautilus is a development stage life sciences company creating a platform technology for quantifying and unlocking the complexity of the proteome. Nautilus’ mission is to transform the field of proteomics by democratizing access to the proteome and enabling fundamental advancements across human health and medicine. To learn more about Nautilus, visit www.nautilus.bioInitial Investment2018Based in Seattle, Washington, Nautilus is a development stage life sciences company creating a platform technology for quantifying and unlocking the complexity of the proteome. Nautilus’ mission is to transform the field of proteomics by democratizing access to the proteome and enabling fundamental advancements across human health and medicine. To learn more about Nautilus, visit www.nautilus.bioFoundersSujal Petal
Parag MallickInvestment JourneyPublic June 2021
NASDAQ: NAUTInitial Investment2018 -
Ovation is a next-generation clinical informatics company.Initial Investment2019Ovation is a next-generation clinical informatics company.
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Proof is a startup working to make powerful CRISPR-based molecular testing affordable and accessible to everyoneInitial Investment2020Proof is a startup working to make powerful CRISPR-based molecular testing affordable and accessible to everyoneFoundersFeng Zhang
Jonathan Gootenberg
Omar Abudayyeh
Siddharth ShenaiInvestment JourneyAcquired by Ginkgo Bioworks
2024Initial Investment2020 -
TwinStrand Biosciences is a Seattle genomics company building a platform around Duplex Sequencing, a proprietary process that helps physicians, patients and drug researchers make life saving decisions faster based on DNA data.Initial Investment2019TwinStrand Biosciences is a Seattle genomics company building a platform around Duplex Sequencing, a proprietary process that helps physicians, patients and drug researchers make life saving decisions faster based on DNA data.
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Vilya is an AI enabled biotech company leveraging advanced computational approaches to design novel macrocycles with atomic-level accuracy and enhanced drug-like properties.Initial Investment2024Vilya is an AI enabled biotech company leveraging advanced computational approaches to design novel macrocycles with atomic-level accuracy and enhanced drug-like properties.